I think I can say the same of English. The only words that I can think of that were used so widely that they ended up losing some of their strength and even ended up being used as terms of endearment within the offended group…were originally incredibly homophobic or racist.

They still carry their weight as insults…probably even more than they did at peak off-label use because they are used so much more sparingly now.

South Park even did an episode for each of them.

They were the final joke in an amazing Derrick Comedy (Donald Glovers old sketch troupe) skit (Spelling Bee) for chrissake.